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The Virus and its Components 


[CLICK ON THUMBNAIL FOR LARGER PICTURE]
(Labelled drawings of HBV byY.H.Kao) 


Contents:
1.  Fast Facts (Click Here)
2. The Antigens (Click Here)
3. The HBV Particles (Click Here)
4. Interpretation of Hepatitis B Markers (Click Here) 


1. Fast Facts:


2. The Antigens:

Subcontents:
1.  Hepatitis B surface antigen, HBsAg (Click Here)
2. Hepatitis B core antigen, HBcAg (Click Here)
3. Hepatitis B 'e' antigen, HBeAg (Click Here)

1. Hepatitis B surface antigen (HBsAg):

2. Hepatitis B core antigen (HBcAg):

3. Hepatitis B 'e' antigen (HBeAg):



3. The HBV Particles:

Subcontents:
1. The Dane Particle (Click Here)
2. The Spherical and Tubular Particles (Click Here)

1. The Dane Particle:

2. The Spherical and Tubular Particles:



4. Interpretation of Hepatitis B Markers:
 

HBsAg HBeAg Anti-HBe Anti-HBc 
IgM
Anti-HBc 
IgG
Anti-HBs Intepretation         
+ + - - - - Incubation period
+ + - + + - Acute hepatitis B or persistent carrier state
+ + - - + - Persistent carrier state
+ - + +/- + - Persistent carrier state
- - + +/- + + Convalescence 
- - - - + + Recovery
- - - + - - Infection with HBV without detectable HBsAg
- - - - + - Recovery with loss of detectable Anti-HBs
- - - - - + Immunization without infection, repeated exposure to antigen without infection, or recovery from infection with loss of detectable anti-HBc

References:
El-Fadil E Omer, 1995, Clinical significance of markers of hepatitis B
Robert's HBV Page
Hepatitis B virus (HBV) Overview
Ivan Roitt, Jonathan Brostoff, David Male, 1993, Immunology, 3rd Edition
Neil A. Campbell, 1993, Biology, 3rd Edition 



For more Information :
Dr Sing Kong Yuen

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