11, 2010. I reviewed the 3 cases to find
whether they are linked to the male gender.
Dogs over 6 years of age are more likely to
develop tumours than younger ones. The
following three cases are recorded to
educate dog owners and help veterinary
students in their studies.
1. Maltese, Male Dog, 18 years old
Circum-anal tumour above anus
One right testicular tumour 3.5 cm x 2.5 cm x 2.0
cm was sent to the Laboratory for
Due to economic reasons, I submitted the
testicular tumour and not the other
atrophied scrotal testicle.
Histopathology Report: Malignant tumour
compatible with a seminoma.
Interstitial Cell Tumours and Seminomas are
reported to produce excessive female
hormones called estrogen. This dog had a
very good coat. Could it be due to excessive
Maltese dog had circum-anal and testicular tumours
survived the anaesthesia and electro-surgical
excision of the tumours
The circum-anal tumour
is more common in male, non-neutered dogs.
Neutering your male dog at a young age will
have reduced the chances of the dog
developing circum-anal tumours and
2. Labrador Retriever, Male Dog, 6 years.
Retained or undescended left testicle grew
explosively to half the size of a tennis
ball while the right testicle was shrunken
(atrophied). Sent both for histopathology.
The dog goes home tomorrow (5th day after
neutering). Blood tests and histopathology
the appearance, the testicular tumour is a
Sertoli cell tumour. Sertoli cell
tumours tend to grow very large. They are
firm, white or greyish and multinodular. The
rate of metastasis is reported to be less
than 10%. Early removal will give the
dog good chances of survival. I believe that
this 6-year-old dog's testicular tumour had
been detected at an early stage* by the
father or family member. If the
histopathology results show a diffuse
subtype as contrasted to the intratubular
subtype. We have to wait and see. A young
lady owner is concerned.
Around 1/3 of dogs with Sertoli cell
tumours show signs of hyperestrogenism
(feminization, gynecomastia, atrophy
of the contralateral testicle,
squamous metaplasia of the prostate
and prostatitis, symmetrical alopecia
from genital area to cranio-dorsally
and bone marrow atrophy.
In bone marrow atrophy - initial
transient increase in granulocytes and
and granulocytopenia. Death is
bacterial infections and bleeding.
Vet undergraduates in the 4th year
may be interested to review the
blood test results of this case at:
Follow up: Sertoli cell
testicular tumour in a dog
Labrador Retriever had atrophy of the
contralateral testicle, prostatitis
(ping-pong ball sized prostate and pain on
digital rectal examination, takes a long
time to pee).
An excellent report on canine testicular tumours is at:
Gigantic cheek tumour excised
electro-surgery in June 2010
checked the anaesthetic records for
excision of the cheek tumour (4.5 cm x
4.5 cm x 0.8cm) in June 2010. It was excised by
electro-surgery for reference. Blood
test results were normal. Dog's
bodyweight was 12.3 kg.
Anaesthetic was domitor 0.2 ml IV.
Zoletil 100 0.1 ml IV. Body tremors
started. Gave Atropine 0.5 ml IV.
Tremors stopped. Surgery done.
Antisedan 0.2 ml IV. Dog woke up fast.
is a white lump in the same area of his
previous tumour," the young lady said today.
"He would not allow me to open his mouth. I
saw it when he yawned." The dog would not
permit me and my assistant Mr Saw to open
his mouth too. He jerked away suddenly when
I gripped his upper jaw. No point fighting
and getting bitten. I will sedate and check
mouth and teeth. Recurrence of oral tumour
likely. Did not send the previous tumour for
histopathology to reduce the veterinary
costs for the owner.
The dog had no fever but vomited and had
diarrhoea 4 X yesterday. The dog will be
treated for gastroenteritis first before any
exploration of the mouth.
"Oral tumours are associated with the many
years of poor dental hygiene," I said to the
young and slim lady who does sales. "My
advice to neuter him is not to prevent
recurrence as this oral tumour. I have not
heard of any scientific studies regarding
neutering and oral tumours. However, any dog
over 6 years of age is likely to develop
tumours. Since your dog has a large cheek
tumour, I advised neutering to prevent
"it is well known that neutering of the male
dogs do prevent or lower the incidence of
circum-anal tumours and the development of
testicular tumours in testicle that have not
come down from the body into the scrotal
I doubt that this young lady know what I am
talking about. I elaborated: "Since this dog
has developed such a large oral tumour, it
is best to remove his testicles in case he
develops testicular tumour. I am not
guaranteeing that castration will prevent
recurrence of the oral gum tumour and mouth
The dog was warded, given the IV drip and
medication for diarrhoea and vomiting. The
oral tumour was excised by electro-excision.
It was smaller replicate of the earlier
tumour. A picture will be posted
3 male dogs had tumours. Would they have
developed such tumours in old age if they
had been sterilised?
Case 1 - Maltese not neutered.
Malignant Seminoma and Circum-Anal tumour.
During his old age, he developed testicular
tumour (malignant) seminoma and circum-anal
tumour. Both were removed and the dog had no
anaesthetic problems although he was 18
years old. I used isoflurane gas only.
Neutering would have prevented such tumours
Case 2 - Labrador Retriever not
neutered. Testicular Tumour - Sertoli
Cell Tumour probably with Interstitial Cell
Surprisingly, at 6 years of age, he
developed the testicular tumour so rapidly.
Testicular tumours occurs in older dogs
and the median age is said to be 10 years. Studies have associated
testicular tumours to develop in undescended
testicles (cryptorchidism) in man and male
Case 3 - Miniature Schnauzer not
neutered. Oral tumour was large like
the S$1.00-coin, measuring like a disc 3 cm
x 3 cm x 0.5cm. Oral
tumours develop due to poor oral hygiene in
dogs and man, according to several medical
reports. There is no association with
neutering or no neutering. Teeth cleaning
every alternate daily and yearly dental
check up most important for your dog if you
want to prevent oral tumours from developing
in your dog. The tumour recurred like a disc
2 months later and was excised. I sent the
tumour for histopathology. The report was
not malignant. Will provide details later.
Dog owners who do not want to neuter their
male dogs for various reasons will need to
spend time every week to examine he lower
part and genitals of the dog to ensure that
they don't develop testicular or circum-anal
tumours. Get them removed by your vet early
if they do occur. When tumours form, early
neutering saves lives. In the 3 cases,
neutering would be useful in Case 1 and Case
2. In Case 3, it is believed that poor oral
hygiene over the life-span of the dog led to
tumour formation but it is hard to
substantiate this hypothesis.